Science themes

The Rosalind Franklin Institute will be driven by research in five scientific themes, each working to develop and deliver tools which enable breakthrough research from academic and industrial communities.

The Institute will not work on projects which could be undertaken in other facilities or institutes – it will focus exclusively on problems where physical science technology can enable significant changes in our abilities to answer biological problems with applications in industry.

The Institute is working to establish roadmaps for activity in the five key scientific themes set out in our business case. These roadmaps will drive our investment in new equipment for the Rosalind Franklin hub building, and will establish collaboration with academic partners both within the ten universities who form our joint venture partnership, and others from the wider academic community.

Cross cutting themes in automation, artificial intelligence, data handling, imaging and links with central facilities (synchrotrons, X-FEL facilities, lasers, neutron sources and others) and industry, are vital to the Institute’s remit, and the theme leads are working together to build networks which address these issues.

To collaborate with the Institute in any of our five themes, please contact info@rfi.ac.uk, indicating your area of interest.

Scientific themes:

Biological Mass Spectrometry  integration of data from omics platforms – omic data fusion; next generation of instruments and detectors.

Correlated imaging – using X-rays, electrons and photons, development of UK’s first pulsed electron microscope, moving from static to time-resolved study of drug take-up.

Imaging with Sound & Light – non-invasive photo-acoustic diagnostic techniques.

Next Generation Chemistry for Medicine – speed up drug discovery and improve efficient translation.

Structural Biology – improved sample preparation and delivery, detector R&D, common standards for sample exchange.